GliONET. White Paper on the Multidisciplinary Management of Glioblastoma
This White Paper has been developed with the aim of providing a practical, concise, and multidisciplinary
guide for the management of patients with glioblastoma. Thanks to the collaboration of a broad and
carefully selected group of specialists from across the country, this document tries to bring together the
best available evidence and current clinical guidelines to support decision-making in real-world clinical
settings. It covers the full spectrum of specialties involved in the diagnosis and treatment of glioblastoma
—including neurosurgery, neurology, medical oncology, radiation oncology, neuropathology, and
neuroradiology— ensuring a comprehensive and coordinated approach.
Contributors were selected based on their recognized experience and active involvement in the care of
these complex patients, representing institutions from all regions of the national healthcare system.
White Papers are designed to distill expert knowledge into accessible and actionable recommendations.
Glioblastoma remains one of the greatest challenges in oncology, due to its aggressiveness, heterogeneity,
and the urgent need for timely, individualized management. In this context, the goal of this publication is to
serve as a quick-reference resource for clinicians —particularly those with less experience in this field—
offering clear, practical information to facilitate optimal patient care from diagnosis through treatment and
follow-up.
We hope this initiative contributes to improving the consistency and quality of care for all patients affected
by this devastating disease.
White Paper on the Multidisciplinary Management of Glioblastoma
Juan Manuel Sepúlveda and María Martínez García
Coordinators of the White Paper on the Multidisciplinary Management of Glioblastoma